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Anticancer drug discovery: A family of enzymes  

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When doctors hurl toxic death at cancer cells, often a few will survive and come back. A family of enzymes called KDM5 histone demethylases is emerging as important for this resilience and drugs that inhibit KDM5 enzymes could be active in treating several types of cancer. A team of investigators obtained detailed structural information, showing how inhibitors of the KDM5 family interact with their targets by building a molecular model of the KDM5A enzyme, along with an inhibitor bound in the active site. Their findings could inform efforts to design more potent and selective anticancer drugs.

Image credit: From Horton et al, Cell Chem Bio (2016)

 
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Blue jet lightning  

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This is the first image ever captured of blue jet lightning. It was taken at Arecibo Observatory in Chile. A team of researchers at Arecibo captured video evidence from the ground of this lightning phenomenon known as blue jet. The discovery is the first ground-based evidence linking the ionosphere with cloud tops in blue jet events. According to Victor Pasko of Penn State University, an electrical engineer working at Arecibo, pilots and others reported observations of red sprites and blue jets long before the first one was captured on video, and numerous undocumented reports of similar phenomena have appeared in scientific literature for over a century.

Image credit: Victor Pasko, Penn State University

 
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New Mars rover is GO for 2020 says NASA  

This time we'll hear the sounds of Mars, if the enhanced Sky Crane works

All being well, NASA will launch the successor to Curiosity Rover in 2020. And this time the agency hopes to prepare samples for an as-yet-blue-sky manned mission that could one day return them to Earth for analysis.…

 
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Happy 50th birthday, optical fibres for telecoms  

In July 1966, Charles Kao looked into glass and saw the future of telecoms

One of the seminal developments in modern telecommunications turns 50 years old this month: the paper that bootstrapped the world of optical fibre communications.…

 
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http://twitter.com/gangactor/status/754845295893094400 
#wildlife trade #Tigers #CITES #Thailand #Trafficking #TigerTemple #Biodiversity #conservation #endangered #species https://t.co/BxQaIrR2Em 
https://t.co/BxQaIrR2Em 

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Clockwork Orange  

ArtGordon1 posted a photo:

 
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Africa's MeerKAT looks at the sky, surprises boffins with 1,300 galaxies  

SKA precursor publishes 'first light' images

The operators of the MeerKAT radio telescope in South Africa have switched on its first 16 dishes and, pretty much immediately, spotted more than 1,200 new galaxies.…

 
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40-year-old chorus frog tissues vital to Louisiana hybrid zone study  
Researchers are shedding light on how often and where species hybridize through time, thanks to the rediscovery of 40-year-old tissue samples preserved at the LSU Museum of Natural Science. In a recent study, they show that two species of chorus frogs now form hybrids across a much wider area of Louisiana and Mississippi than they did just 30-40 years earlier. A widening area of hybridization has important implications for the future of these species and suggests that recent alterations to their environment have affected their fitness or dispersal ability.  
gaia  

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Ptarmigan in Colorado have varied reproduction, not likely linked to warming trends  
Ptarmigan, which live in cold ecosystems, are not strongly affected by fluctuations in seasonal weather at two populations studied in Colorado, report scientists.  
gaia  

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World's greatest concentration of unique mammal species is on Philippine island  
Luzon, the largest island in the Philippines, is home to the world's greatest concentration of unique mammal species -- 93 percent of the land mammals there are found nowhere else. A new paper announces that 52 of the island's 56 non-flying mammals live nowhere else in the world. Of these 56 species, 28 were discovered during the course of the 15-year project. The study provides insight into how island evolution works, and could inform future conservation efforts.  
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Photos of the Day: July 17, 2016  

Explore the news of the day with these images from around the world.  
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All There Is  

danjama posted a photo:

I took another walk to my new favourite local spot.

 
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pornhashtag.com  

spectar69 posted a photo:

VISIT: goo.gl/RX2WI1

 
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